As an undergraduate student at Olin College I worked on a research project on the subject of improved radiotherapy targeting. Methods to treat prostate and other location-specifric cancers are increasinly accurate, however this accuracy is wasted, and can be detrimental, when not dosed correctly for the region in question and if mis-applied. Methods to test a particular approach prior to treatment help validate the treatment plan and ensure that treatment is not harming non-target tissue. These methods typically use a basic housing with multiple detectors to measure radiation mounted inside a basic human body shape.
In this research we examine methods to support targeted radiotherapy radiation detection by creating a housing for dosimetry radiation measurement chips that can be tailored to the specific shape and location of a patients tissue of interest, mounted within a realistic human phantom. The published paper below describes details of this work.
In my role in the project I defined a method to use MRI scans of a patient to generate 3D CAD models of the tissue in question. I then designed a housing that can accomodate individual variations in tissue shape and location to support more accurate radiation mesurement chips.
The images above show an example of the appraoch to generate 3D images from MRI scans. The human phantom has been modified to support insertion of the custom housing of this measurment unit, which is shown in more detail in the paper linked below.